Pfizer and Novo Nordisk Embroiled in Legal Battle Over Metsera Acquisition

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Pfizer and Novo Nordisk Embroiled in Legal Battle Over Metsera Acquisition

Pharmaceutical giants Pfizer and Novo Nordisk are locked in a high-stakes legal confrontation over the acquisition of obesity drug developer Metsera. The dispute has escalated rapidly, with Pfizer filing multiple lawsuits to block Novo Nordisk's unsolicited bid, claiming anticompetitive practices and breach of contract.

Novo Nordisk's Surprise Counteroffer

Novo Nordisk shocked the industry by announcing an unsolicited offer to acquire Metsera for $6.5 billion upfront, with potential milestone payments bringing the total to $9 billion. This bid comes more than a month after Pfizer had seemingly secured a deal to purchase Metsera for $4.9 billion upfront, with an additional $2.4 billion in potential milestone payments.

Metsera's board described Novo Nordisk's offer as "superior," triggering a four-day window for Pfizer to counter. The Danish company's bid represents a significant premium over Pfizer's original offer, with Novo Nordisk proposing $56.50 per share in cash plus $21.25 in contingent value rights (CVRs).

Pfizer's Legal Counteroffensive

In response to Novo Nordisk's bid, Pfizer has taken aggressive legal action. The company has filed two separate lawsuits in the Delaware Court of Chancery:

  1. A lawsuit against Metsera and Novo Nordisk, alleging breach of contract, breach of fiduciary duty, and tortious interference.

  2. A second lawsuit against Novo Nordisk, Metsera, and Metsera's lead shareholders, including venture funds operated by ARCH Venture Partners, alleging an "anticompetitive conspiracy" in violation of the Clayton Antitrust Act.

Pfizer claims that Novo Nordisk's offer is "reckless and unprecedented" and "structured in a way to circumvent antitrust laws." The company has requested a temporary restraining order to prevent Metsera from terminating its existing merger agreement with Pfizer.

Implications for the Obesity Drug Market

This legal battle underscores the intense competition in the rapidly growing obesity drug market. Metsera's pipeline includes several promising candidates:

  • MET-097i: A phase 2b injectable GLP-1 receptor agonist with potential for monthly dosing
  • A monthly injectable amylin analog
  • An oral GLP-1 agonist designed to overcome limitations of existing small molecules

The acquisition of Metsera would significantly bolster either Pfizer's or Novo Nordisk's position in the obesity treatment landscape. Novo Nordisk, already a dominant player with its blockbuster drug Wegovy, seeks to "maximize the potential of Metsera's complementary portfolio and capabilities." Pfizer, on the other hand, views the acquisition as crucial to its re-entry into the obesity drug market following setbacks in its internal pipeline.

As the legal proceedings unfold, the outcome of this high-profile dispute will likely have far-reaching consequences for the future of obesity drug development and competition in the pharmaceutical industry.

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